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In 2013, DFP significantly improved motor function in patients with PD in a 12-month phase II clinical trial of PD, but patients who continued to take DFP showed diminished improvement in motor function as well as reduced Neutrophils and granulocyte deficiencies (Martin-Bastida et al., 2017)

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doi: 10.1016/s0014-5793(03)00664-1