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In this study, we have revealed the importance of the glutamate-generating metabolism, as shown by a complete depletion of glutamine (Gln) in the medium during H
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Abbreviations: COPD: Chronic Obstructive Pulmonary Disease, T2D: Type 2 Diabetes, GDF15: Growth differentiation factor 15, ARDS: Acute respiratory distress syndrome, AMPK: AMP-activated protein kinase, NLRP3 : NLR family pyrin domain containing 3, SIRT1 : Sirtuin 1, GLP-1RAs: Glucagon-like peptide-1 receptor agonists, DPP-4is: Dipeptidyl Peptidase-4 inhibitors, FVC: Forced Vital Capacity, DLCO: Diffusing capacity for carbon monoxide, NF-κB / Nrf2 : Nuclear Factor kappa-light-chain-enhancer of activated B cells/Nuclear factor erythroid 2-related factor 2, LPS: Lipopolysaccharides, SGLT-2 Inhibitors: Sodium–Glucose Cotransporter-2 inhibitors, ↑ indicates increase/enhancement, ↓ indicates decrease/reduction
