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Additionally, we investigate the effects of GABAergic pharmacological agents on mood, and demonstrate that these compounds have complex effects that do not universally support the idea that reduced GABA neurotransmission is at the root of MDD
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has demonstrated that deletion of autophagy related genes (ATG), Atg5 and Atg7 in KRAS driven mouse models of pancreatic ductal adenocarcinoma, impedes progression of precursor lesions such as pre-malignant intraepithelial neoplasia (PanINs) to a late stage malignant tumor [30]
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