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S4：将8.00g中间体3（23.74mmol）加入250mL反应瓶中，加入32g甲醇，再加入0.4gPd/C，控制温度25-35℃，加压氢化2小时，TLC点板观察，反应完全。S4: Add 8.00g of intermediate 3 (23.74mmol) into a 250mL reaction flask, add 32g of methanol, and then add 0.4g of Pd/C, control the temperature at 25-35°C, pressurize hydrogenation for 2 hours, observe by TLC plate, the reaction is complete