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While BPC-157 and TB-500 are still under investigation and not approved for therapeutic use, preclinical studies have explored their potential in a range of biological contexts

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Other mechanisms underlying excessive ER-phagy Loperamide and pimozide induce excessive ER-phagy in patients with GBM and upregulation of cholesterol and lipid anabolism, leading to the accumulation of cholesterol and lipids (predominantly ceramide) in lysosomes [47]