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To investigate further, we used CD8-cre mice to achieve CD8 + T cell–specific GPX4 cKO (CD8-cre + gpx4 fl/fl ), revealing sufficient suppression of tumor growth by host GPX4-deficient CD8 + T cells (Figure 1L)

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[16] [17] [18] It was also established that GHK-Cu stimulates both the synthesis of metalloproteinases, the enzymes which break down dermal proteins, and their inhibitors (anti-proteases)