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In addition to its photodynamic activity, hypericin has demonstrated antidepressant effects, possibly through the modulation of neurotransmitters such as serotonin, dopamine, and norepinephrine, thereby influencing mood regulation.14–17 Furthermore, extensive research highlights hypericin’s antiviral and antimicrobial effects, which inhibit viral replication and bacterial growth, positioning it as a potential therapeutic agent in infectious disease management.18–20 Recent studies also suggest that hypericin exhibits anti-inflammatory properties, potentially via the inhibition of pro-inflammatory mediator production, thus broadening its therapeutic applications.21,22 However, the sensitivity of hypericin to light necessitates proper storage and handling under low-light conditions to preserve its stability
